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Polynucleotides

This is a revolutionary skin/undereye rejuvenation treatment using ultra purified and sterilised DNA fractions, in the form of a gel, which is injected into a given area as a biostimulator. The polynucleotides initiate your body’s natural fibroblast production, resulting in increased collagen and a thicker, healthier epidermis (upper skin layer).

They are synthetically aggregated in laboratories with the nucleotides extracted from Salmon sperm. This is because the DNA contains similar codes to human DNA. This however has no relation to fish allergies and the treatment has so far proven to be hypoallergenic.

People with dark circles, poor skin quality or very mild hollowness can all benefit from this. If you have a lot of hollowness, it is likely we will suggest tear trough filler afterwards as the polynucleotides will not create much volume. Once the polynucleotide treatment has been carried out, there is initial swelling which should not be confused for results. Because this treatment stimulates your own body, results are typically seen 60 days after the initial treatment.

If you have a lot of accompanying hyperpigmentation, we will usually advise having polynucleotides with undereye mesotherapy (with the added effect of brightening hyperpigmentation).

Polynucleotides are good alternative for those who are not suitable or keen on having typical tear trough filler and they do not carry some of the risks associated with dermal filler.

We suggest bringing a pair of sunglasses so you can conceal any initial swelling or bruising.

Duration & Longevity

The appointment takes around 45 minutes, including numbing time.

We recommend a course of minimum 3 sessions, carried out 2-4 weeks apart for best results.

As we can never halt the skin’s ability to produce pigment in this area, we recommend 1 maintenance session every 6-9 months to keep the area looking bright.

Procedure

It can be a bit uncomfortable however we numb the skin prior to the treatment with numbing cream. Local anaesthetic is also added into the injected solution to reduce any pain.

We also do not use needles in this delicate area, to reduce trauma and discomfort. Instead we use a micro-cannula to deposit the solution. This is blunt ended and uses only a single entry point on both sides, thereby reducing trauma and minimizing risk.

The result can be seen gradually over the next few weeks and is a cumulative result based on a course of treatments.

Downtime

As we are placing these ingredients superficially into the skin in the area, moderate swelling is expected on the day and for most people, is largely gone by the next morning as it is absorbed into the skin. Some patients, however, do still have a small degree of swelling for a few days after the treatment. This is generally not bad enough to mean they can’t go to work or carry on as usual.

Common Misconceptions

It is important to realize that dark circles can be influenced by so many different factors such as:

  • Thin skin under the eye

  • Hollowness due to genetics or the ageing process.

  • Hyperpigmentation

  • Vitamin Defiencies

It is thus important to have a consultation first and also to be realistic with your expectations. If you are affected by all of those four factors above, yet only address e.g. the hyperpigmentation with undereye mesotherapy, you cannot expect the dark circles to be suddenly gone.

In the same way, people often assume once hyperpigmentation is treated, the problem is solved. Unfortunately, no treatment can get rid of it completely but if we can brighten the area, we can improve the dark circle appearance.

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Dark Circles

Signature Treatment

One of the most common areas that patients seek treatment for is their dark circles. It is unfortunately however, one of the hardest areas to treat simply because there are so many influencing factors which contribute to dark circles such as:

  • Thin skin under the eye: This means blood vessels underneath are more visible and can give the skin a grey-blue tinge. This can be improved with undereye polynucleotides.

  • Hollowness due to genetics or the ageing process. As we age, from our mid 20’s, our undereye hollows become deeper and our mid cheeks become flatter. This can mean the area is more shadowed as a result giving an overall darker appearance. This can be improved with tear trough filler.

  • Hyperpigmentation: True hyperpigmentation is caused by overactive melanocytes laying down more melanin which is also triggered by sun damage and lack of SPF. This pigment is usually extremely dense, and hard to shift. We can aim to lighten and brighten the area using undereye mesotherapy.

  • Vitamin Defiencies such as iron, B12, E and D have all been linked to dark circles and again, can present as a more greyish colour in anemics for example.

It is thus important to have a consultation first and also to be realistic with your expectations. If you are affected by all of those four factors above, yet only address e.g. the hyperpigmentation, you cannot expect the dark circles to be suddenly gone. Dark circles can be improved, but never eliminated. All of the examples shown in this gallery have been treated with multiple modalities for best results.

Treatments for dark circles often take multiple sessions and multiple different treatment forms e.g. undereye mesotherapy sessions to lighten the area followed by filler to correct the hollowness.

Undereye mesotherapy gives gradual results over at least 3 sessions whereas the results from the filler are instant, and generally last around 9-12months. Each time you have this done, the results will last longer as the filler induces collagen into the region over time.

It can be a bit uncomfortable however we numb the skin prior to the treatment with numbing cream.

We also do not use needles in this delicate area, to reduce swelling/pain and also to be safe and minimize complications. Instead we use a micro-cannula to deposit the filler. This is blunt ended and uses only a single entry point on both sides, thereby reducing trauma and minimizing risk.

The result can be seen instantly for filler and gradually with undereye mesotherapy, but tends to improve over the next 3-4 weeks post treatment.

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